If you decide to join the bone sub-study, you will have a bone scan, called a “high-resolution peripheral quantitative computed tomography” (HR-pQCT) scan. This scan uses special scanners and computers to measure the density of the bones in your arms and legs. These scans provide more detailed X-ray images than a standard bone density test. Right now, this scan is used for research only, however, the results will be shared with you. Researchers will use this scan to learn more about how denosumab affects bone health. There is no charge for this extra bone scan.
Note: Currently, this study is only offered to study participants at some sites due to limited scanner availability.
What participation involves: During the HR-pQCT scan, you will be asked to sit in a chair and rest your arm or foot in the scanner. You will be asked to hold still for 2 to 3 minutes during each scan.
The HR-pQCT scan uses a very small amount of radiation to do its measurements. The total amount of radiation exposure would be the same as what you would normally get from natural background sources in the earth and the sky in less than 1 month.